The major (such as Computer Science or Biological Sciences) is exactly the same regardless of which college you attend: the major requirements, professors, classes, rigor, and research opportunities are all the same. The difference is in the requirements outside of the major, as each college has different distribution requirements.
Students with an interest in biology have many exciting choices at Cornell. Four of the undergraduate colleges (College of Agriculture and Life Sciences, College of Arts and Sciences, Cornell Duffield College of Engineering, and the College of Human Ecology) offer biology programs.