The major (such as Computer Science or Biological Sciences) is exactly the same regardless of which college you attend: the major requirements, professors, classes, rigor, and research opportunities are all the same. The difference is in the requirements outside of the major, as each college has different distribution requirements.
Some of the undergraduate colleges at Cornell ask applicants to report the highest calculus class they will complete by the time they graduate from high school. If you are applying to the College of Agriculture and Life Sciences (CALS), the College of Arts and Sciences, the Cornell Duffield College of Engineering, the Cornell Jeb E. Brooks School of Public Policy, or the Cornell SC Johnson College of Business, you will be required to answer this question. Here are some guidelines that may be helpful in doing so:
